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貨號(hào) | 品牌 | CAS | 規(guī)格 | 銷(xiāo)售價(jià)(RMB) | 折扣價(jià)(RMB) | 備注 | 數(shù)量 |
ABP0184-100μL | Abbkine | 無(wú) | 100μL | 1998 | 1998 | 無(wú) |
產(chǎn)品英文名稱 | E2F-1 Polyclonal Antibody |
免疫原 | 合成多肽 :人源蛋白,AA:100-170 |
宿主 | 兔 |
反應(yīng)性 | 人, 大鼠, 小鼠 |
應(yīng)用 | ELISA, IF, IHC-P, WB |
實(shí)驗(yàn)建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IF:1:50-1:200,IHC-P:1:50-1:300,ELISA:1:10000-1:20000。 |
克隆性 | 多克隆 |
純化工藝 | 使用表位特異性的免疫原,通過(guò)親和層析,從兔抗血清中親和純化抗體。 |
產(chǎn)品形式 | 液體溶液 |
濃度 | 1 mg/ml |
分子量 | 70 KD |
儲(chǔ)存緩沖液 | PBS緩沖液(pH 7.4),含有0.02%疊氮化鈉(防腐劑)和50%甘油。 |
保存建議 | 自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。 |
運(yùn)輸條件 | 藍(lán)冰運(yùn)輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類(lèi)或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔(dān)任何責(zé)任。 |
背景 | The protein encoded by E2F1 (E2F transcription factor 1) is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP, a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
基因ID | 1869 |
別名 | E2F1 RBBP3 |
其它 | 該抗體可檢測(cè)內(nèi)源蛋白 |
蛋白質(zhì)ID | Q01094 |
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