促分裂原活化蛋白激酶激酶1/2 (phospho Ser218/222)多克隆抗體

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產(chǎn)品英文名稱	MEK-1/2 (phospho Ser218/222) Polyclonal Antibody
免疫原	合成多肽：人源蛋白MEK-1/2，磷酸化多肽，中心氨基酸為S218/222.
宿主	兔
反應(yīng)性	人, 大鼠, 小鼠
應(yīng)用	ELISA, IHC-P, WB
實(shí)驗(yàn)建議	最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：WB：1:500-1:2000，IHC-p：1:100-1:300，ELISA：1:5000。尚未在其他應(yīng)用中測(cè)試。
克隆性	多克隆
純化工藝	使用表位特異性的免疫原，通過(guò)親和層析，從兔抗血清中親和純化抗體。

產(chǎn)品形式	液體溶液
濃度	1 mg/ml
儲(chǔ)存緩沖液	含有50％甘油，0.5％BSA和0.02％疊氮化鈉的PBS緩沖液。
保存建議	自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件	藍(lán)冰運(yùn)輸
警告	本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔(dān)任何責(zé)任。

背景	Mitogen-activated protein kinase 1 encoded by MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs， act as an integration point for multiple biochemical signals. Mitogen-activated protein kinase 1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway,Mitogen-activated protein kinase 1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
基因ID	5604/5605
別名	MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k
其它	該抗體可檢測(cè)內(nèi)源蛋白
蛋白質(zhì)ID	Q02750/P36507